The Packers open the home portion of their 2010 schedule today at noon against the Buffalo Bills.

They'll try to win their fourth consecutive home opener for the first time since Curly Lambeau's teams accomplished the feat from 1938-'41.

Green Bay will also come into the game looking to replace running back Ryan Grant who was lost for the season last week when he injured his right ankle against Philadelphia.

"This is something we have to deal with and move forward from as a team. We have confidence that our other players will step up and meet the challenge of these losses."

Brandon Jackson will start at running back against the Bills.

Packers (1-0) vs. Bills (0-1)
Lambeau Field

Kickoff: 12 p.m.

Broadcast: TV -- CBS (58) with Spero Dedes (play-by-play) and Randy Cross (color commentray); Radio -- Packers Radio Network/WTMJ-AM (620) with Wayne Larivee (play-by-play) and Larry McCarren (color commentary).

Line: Packers by 14

All-time series: 11th meeting (Bills lead, 3-7).

Last meeting: Nov. 5, 2006 -- Buffalo 24, Green Bay 10.

Head coaches: Green Bay -- Mike McCarthy (40-28, fifth season); Buffalo -- Chan Gailey (18-17, 3rd season / 0-1 with Bills).

Notes: Packers opening 54th season at Lambeau Field ... Buffalo making its fourth visit to Green Bay ... Bills have played twice in Milwaukee (1982, '91) ... Packers have won three consecutive home openers; trying to win fourth for first time since '96-'98) ... Sunday is first time Packers have opened at home against AFC opponent since '05 ... Bills coming off season-opening loss to Miami ... Buffalo OLB coach Bob Sanders was Packers' defensive coordinator from '06-'08 ... WR Donald Driver has 16 receptions for 206 yards and two touchdowns against the Bills.